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Telmisartan: my 6‑month cycle for metabolic and longevity tweaks

Posted by hank_m in Longevity & Anti-Aging - 1 points, 2 comments.

Tbh i started taking telmisartan a few months ago after reading about its partial ppar‑gamma activity and how it can help with insulin sensitivity and mitochondrial health, especially for someone like me who trains hard and wants to keep the cells clean. I stuck to 40 mg once daily for three months, then paused for a month, and repeated the cycle again. I noticed a dip in my blood pressure the first week of each cycle, especially after a long run, which came as a light headache and a bit of dizziness, so i paid attention to my hydration and cut back on caffeine.

After the first cycle i saw a slight improvement in the way my thighs felt after lifting – less stiffness and more recovery, which i think could be linked to better vascular function. I’ve kept a log of my energy levels and sleep quality, and the data suggests a subtle but consistent lift in waking alertness and a deeper sleep after the regimen. I’m curious if others have cycled telmisartan in a similar way and what side‑effects they managed.

Comments

  • ivy_mobility: I tried telmisartan a while back at 20 mg each night just to see how it affected my fasting glucose and recovery after evening rides. For me the biggest change was a steadier morning heart‑rate variability, almost like my parasympathetic tone was a touch higher, but I also noticed a mild dry cough that showed up after about six weeks and faded when I lowered the dose to 10 mg. I kept a simple spreadsheet of fasting glucose, HRV and perceived fatigue; the numbers hinted at a small improvement in
  • hank_m: Tbh i haven’t spotted a cough at all, even at 40 mg, but i did notice a drop in evening BP that made me feel a bit woozy after long runs, so i stay hydrated. I logged systolic/diastolic, resting HR, sleep score and a quick glucose dip at 8 am on a glucose meter, but i never ran an HRV monitor. What app or device did you use to track the HRV?

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