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I’ve tried a week of low‑dose rapamycin and it changed my recovery

Posted by hank_m in Longevity & Anti-Aging - 2 points, 2 comments.

Tbh i started a 4‑week rapamycin run after reading about the mTOR stuff in the latest longevity telemedicine posts, thinking it might give my post‑bike recovery a lift, and it ended up sweet as. I took 3 mg once a week on a Sunday after a hard 60‑km ride to tap into the autophagy buzz, hoping the cell‑cleaning would help my muscles bounce back faster. During the first week i noticed my sore quads healing a day or two quicker than usual, and a subtle boost in my sleep quality – i fell asleep faster and woke up feeling less groggy, which helped my focus at work the next day.

I did get a mild mouth sore about halfway through, but it subsided once i stopped the dose for a day, so i kept the schedule. I haven’t yet seen big changes in my skin or visible energy spikes, but i’m still riding through the last two weeks, keeping an eye on the inflammation markers i’ll shoot up in the next blood test. I’d be curious how others feel about cycling with rapamycin.

Comments

  • retiredcole: Tbh I’m a first‑timer too, so I can’t claim full proof, but the pattern you describe matches what a few of us have felt. I’ve been squatting a 3 mg weekly dose on my recovery days, and I did see quads complain less on the next ride and a tangible drop in my post‑work fatigue – less groggy mornings. Mouth sores pop up sometimes, the same way you said, so I cut a day off when it happened. My sleep has steadied too, though I can’t say it’s pure rapamycin; maybe the cycle timing or the bike load ma
  • hank_m: Tbh i’m glad your pattern’s similar, mate, makes the vibes feel more legit, so thanks for that, and it’s good to know the mouth sores are common, so the day‑off trick worked for me too, when i had to skip on the 3‑mg dose after the sore, i still didn’t feel a loss. I’ll try your idea and take it on a fully rest Sunday – no riding – next week to see if the recovery boost is stronger and if the quads feel even lighter, and i’ll note the sleep change again before the blood test.

Community discussion - research and educational context only. Not medical advice.