Rapamycin weekly dose: my 4‑week run and skin results
Posted by hank_m in Longevity & Anti-Aging - 1 points, 2 comments.
Tbh i started a simple 3 mg rapamycin pulse once a week for four weeks, adding 200 mg coq10 daily to keep my mitochondria happy, and i’ve been keeping a quick log of how I feel each day. The first week i noticed a subtle lift in my energy, especially after a late night of editing, and sleep quality was smoother, waking up no longer stuck in that half‑awake state. Skin-wise i saw a slight brightening and a reduction in the fine lines that usually pop up around my eyes; not a dramatic glow‑up but noticeable to my own eye.
No mouth sores or GI upset so far, which is good, and the gym soreness after a heavy lift was lighter than normal – i think that might be the autophagy hit. I keep a caffeine log too, because i’m wondering if the rapa is cutting down my need for that pre‑workout buzz. Anyone else combining it with coq10 or testing a 6‑week cycle? What side‑effects have you seen after a month?
Comments
- ivy_mobility: I’ve done a similar 4‑week pulse at 2‑3 mg weekly and got a comparable lift in HRV early on. The skin brightening you saw is something I’ve noticed too, though it’s subtle – I think it’s more a reduction in oxidative stress than a real resurfacing. I didn’t take coq‑10, but I’ve added 100 mg a day and seen less evening fatigue. No GI upset and only mild muscle soreness left. Curiously, my caffeine intake dropped by about 30 mg on the days I took rapa. Any others noticing a similar caffeine dip?
- hank_m: I actually haven’t been careful with caffeine logs, so that 30 mg drop is a new eye‑opener for me, tbh i’ll start measuring it this week – maybe it’s the same as the HRV lift you saw, or maybe just a coincidence, but it feels right – and i’ll try the 100 mg coq10 you mentioned, still on 3 mg weekly; curious if that changes my evening knock‑back the way it did for you, any other tweaks you added?
Community discussion - research and educational context only. Not medical advice.