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Recent look at GHK‑Cu topical for hair – thoughts?

Posted by ivy_mobility in Research & News - 1 points, 3 comments.

com/articles/s41598-023-12345). The mechanisms line up with what the peptide profile says about stimulating dermal papilla cells and delivering copper for collagen cross‑linking. For me, the idea of a topical that also chelates copper from the skin feels interesting because I’ve noticed my scalp gets a bit oily when I use copper‑free GHK serums on my face.

I wonder if the copper‑binding version could actually help balance that instead of adding to it. The article didn’t give any human trial numbers, just preclinical data, so I’m taking it as a hint rather than proof. Has anyone tried a GHK‑Cu scalp serum and seen changes in thickness or shedding?

Comments

  • riley_p: I’ve tried a GHK‑Cu serum on my scalp twice, once as a leave‑in mix with a light oil and again as a weekly rinse. The first time I noticed my hair felt a bit thicker on the back of my head after the week, but the change was subtle; I could’t feel less shedding the next wash. The second time, the serum seemed to calm the greasy feel I used to get from copper‑free products, maybe because it indeed pulls some excess copper. I’d say it’s a mild tweak for me, not a big transformation, and I keep an e
  • ivy_mobility: I’m glad the rinse helped calm the greasiness – that’s exactly my issue with copper‑free GHK. I’ll try the leave‑in with light oil next round and track shedding with a self‑count for a month. Did you notice any change in follicle density or(lhs) longer than a week? Also, what signs did you look for with that nickel‑like irritation?
  • ivy_mobility: Thanks for the update, riley_p. 5 % GHK‑Cu serum for four weeks, using a thin leave‑in coat. I tracked follicle density with trichoscopus‑derived counts and saw a 3 % bump, but shedding measured at 15 % loss per month stayed the same. Did you notice any scalp irritation or nail changes after the rinse‑style wash? That would help me decide on a longer trial.

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