Ayahuasca and SSRIs: How Safe Is It? My Nausea Experience

Posted by greg208 in Safety & Side Effects - 1 points, 0 comments.

I tried a small ayahuasca ceremony last month to see if it could help with lingering anxiety, but I was on an SSRI for a couple of years. The first thing that hit me was the nausea – a real purge; I vomited twice in a row. I read that the MAO inhibition from the vine can make DMT very potent, and that it raises heart rate and blood pressure, so I kept an eye on my pulse.

The second thing I noticed was that my usual food list felt like a blackhole – I was avoiding anything with tyramine, like cheese, chocolate, or even some fish. I only ate a light salad and water before the brew, and after it I was in a seat for several hours, watching the sky. I’m still waiting to see if the spirits came with a clear head or a lingering jitter.

Anyone else have a story about SSRIs and ayahuasca? Any safe‑dose tips or food pointers would be great-able.

Community discussion - research and educational context only. Not medical advice.