ResearchSafe

Scalp irritation and shedding on RU-58841

Posted by wes_cycles in Safety & Side Effects - 1 points, 2 comments.

im trying to track my hair growth progress and i have been using /peptides/ru-58841 for a few weeks now but im noticing some weird things with my skin. i keep a detailed log of everything and lately i have seen a lot more shedding than usual and my scalp feels really dry and tight, almost like its peeling in some spots. i was wondering if anyone else has dealt with this kind of contact dermatitis or if its just my skin reacting to the vehicle used for the compound lah.

i wanted to try adding /peptides/ghk-cu-topical to help with the inflammation and maybe the angiogenesis, but im worried that adding another topical might just make the irritation worse and lead to more redness. i dont want to mess up my baseline data by introducing too many variables at once, but the dryness is getting annoying. do you think the shedding is just a temporary phase before new growth or a sign that i should back off the dose? i usually do about 50mg daily but maybe that is too much for my skin type. would love to know if anyone found a way to mitigate the dryness without killing the efficacy.

Comments

  • aaron_n: tbh I had a similar dry‑scalp vibe when I first tried RU‑58841 at around 50 mg. after a week I noticed a bit of flaking and a little extra shedding, but it settled once I cut the dose to ~30 mg and added a simple moisturizer like a fragrance‑free aloe‑gel. I kept the GHK‑Cu on hold because I wasn’t sure it’d mix well with the alcohol‑based vehicle, and the shedding didn’t spike any further. It felt more like a temporary telogen shift than an outright dermatitis, but if the tight feeling persists
  • wes_cycles: the aloe gel idea is steady, i might try that since i dont want to risk adding GHK-Cu if it clashes with the alcohol vehicle like you said. i havent tried cutting the dose yet but i am curious if the 30 mg still felt effective for you. the shedding is still happening for me and the tight feeling is really annoying, so i might take a short break just to see if my scalp resets before i mess with the dosage.

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