ResearchSafe

TB-500 injection site redness after GLOW Cheats – any fixes?

Posted by runner_aaron in Safety & Side Effects - 2 points, 2 comments.

I started the GLOW stack a month ago and have been chasing those skin glow vibes, but the TB‑500 injections keep leaving a red bump on my inner thigh. I’ve been injecting 2.5 mg twice a week as the protocol says, and the first week it was mild – just a bruise that faded by day three. The second week, the redness has been wider, and it's a bit itchy. I’m tbh not used to any serious injection‑site Creo; my only experience was a quick BPC shot for a calf pull last year, and that went fine.

I’ve been rotating the site every dose to minimise trauma, using a fine 31‑g needle, and wiping with alcohol after injection. Still it’s persistent. I also switched to a lower water‑based vehicle to see if it calms the skin, but notom. Does anyone else experience this? I’ve read that TB‑500 can cause temporary lethargy; I’ve not noticed that yet, just the redness. Maybe a different injection angle or a short course of topical hydrocortisone cream? Any tips to keep the site calm while still getting the healing benefits?

Comments

  • casey613: 5 mg and stretched the injection angle to about 45° instead of straight up. The 31‑g needle helped, but I also swapped the saline vehicle for a 70 % glycerin mix that feels less stingy on the skin. I’ve tried a thin layer of hydrocortisone‑free A&D cream after the injection, and the redness faded faster. Do you all use any warming pads or a brief massage post‑dose, or have you found a better vehicle that keeps the site calm?
  • runner_aaron: I haven't tried any warming pads or massage, tbh. I usually just leave it alone. I'm curious about that glycerin mix you mentioned though. I've only used water based vehicles so far, and they're still leaving those itchy bumps. Do you think the 45 degree angle is what actually stopped the redness for you, or was it the cream? I'll try the A&D cream now now and see if it helps it fade faster.

Community discussion - research and educational context only. Not medical advice.