TB‑500 dosing timeline for rotator cuff rehab – any stack advice?

Question

I tore my rotator cuff in a heavy‑weight lift a month ago and had arthroscopic repair, then got 4‑weeks of physiotherapy. Since then I started oral BPC‑157 200 µg twice daily to try to speed up tendon healing, and it felt a bit easier when I stretched but pain still lingers. A few friends told me to add TB‑500 injections to the mix, and I’ve read that you usually load twice a week for 2‑4 weeks and then drop to once a week for maintenance. But I’m not sure how that lines up with the oral BPC‑157 – should I alternate days, or give them back‑to‑back? Do you think the BPC‑157 should be stopped at the same time the TB‑500 loading stops, or can the two run in parallel? Also, I’ve heard that people topically apply hyaluronic acid to the shoulder area – does that interfere or help? I’m looking for a real‑world stack that doesn’t require a doctor, but I’d love to hear any practical timelines, things that worked for your own rehab, and any safety notes or side‑effect observations. For me it’s been a steady but slow recovery, and I want to push it in the safest way.

protocol520 · Accepted Answer

I’ve tried the combo in my own rehab after a shoulder injury. I ran BPC‑157 200 µg twice a day for about six weeks, then when the pain got to a 3‑4/10 I started TB‑500 2 µg injections twice a week for four weeks and then once a week. I didn’t stop BPC‑157; kept it through thelgende TB‑500 cycle, thinking the two help each other – one works from inside the tendon, the other from the outside. Topical hyaluronic acid hasn’t slowed me; I applied it after each physiotherapy session and felt more range. No clear interaction, but I kept the spray separate from the injection site. I see mild bruising from TB‑500 and a slight stomach discomfort from BPC‑157, but nothing serious. Do you think a week‑long break between the two would help? Fwiw, I’ve not had any adverse reactions and my range is improving, though my doctor told me to wait a little longer before heavy lifting. 😊

casey613 · Answer

I’m glad you ran the combo for six weeks – that’s more than the six‑week period I’ve used so far, so the extra BPC‑157 might have helped your tendon’s internal signalling while the TB‑500 stitches up the outer layer. I’ll keep my oral BPC‑157 for the whole four‑week TB‑500 loading plus an extra week after, but I’ll schedule the injections on the same days I take the BPC pill, so I don’t get two shots in a row. I’d like to know what needle gauge you used and how much volume per TB‑500 dose – that’s where I’m still unsure, and I want to avoid bruising like you mentioned.

TB‑500 dosing timeline for rotator cuff rehab – any stack advice?

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