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Rapamycin trial for longevity: 6 weeks in – energy shifts and skin notes

Posted by elle_z in Longevity & Anti-Aging - 0 points, 1 comments.

So I started Rapamycin a few weeks back just out of curiosity since I’ve been reading about how it affects aging markers. It’s 3mg once a week via injection, which feels a bit intense but manageable. First thing I noticed was a weird foggy feeling for the first two cycles, like my brain wasn’t quite sharp. Had to up my coffee intake which didn’t help. But by week three, something shifted – my energy levels felt more stable, less of that mid-afternoon crash. Not super hyped, just… steady. Skin-wise, I’ve had dry patches before but they seem less frequent now. Maybe coincidence? Dunno.

Sleep’s been weird too. Went from insomnia to sleeping through the night but with that weird dreamless state where you wake up and your mind’s blank. Not great. Also, I’ve been tracking my NAD+ levels with that at-home kit and they’ve been slightly up, but I’m not sure if it’s the Rapamycin or just random.

The biggest thing is how I feel about it. I know it’s not a magic bullet, but there’s this hope that low-dose stuff might help long-term. My doc said to keep an eye on blood work, which I’m doing. Still, I’m not sure if I’ll stick with it. Side effects are mild but annoying – joint aches sometimes, and that weird metallic taste in my mouth. Would do it again? Maybe, but only if I see clearer signs. Just my two cents, no science here. Always talk to your doctor before trying stuff like this lah.

Comments

  • vo2max_sleep: I tried 2 mg rapamycin once a week orally for about two months and noticed a similar foggy start – felt a bit slower in the mornings and needed an extra espresso to get through my lifting sessions. After week three the mental cloud lifted and my energy felt more even, less of that afternoon dip, though I wasn’t suddenly buzzing. My skin did seem a bit less flaky on my forearms, but I also started using a richer moisturiser around the same time so it’s hard to tell. Sleep stayed fragmented; I’d

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