Adding Amlexanox to My Semaglutide Routine – Early Notes on Appetite and Energy

Posted by weekendnate in Weight Loss & Metabolic - 1 points, 1 comments.

5 mg weekly for about eight weeks and hit a plateau where my appetite crept back up and my weight loss stalled. Curious about the amlexanox mechanism I read about, I started a low dose experiment: 50 mg three times daily with meals, keeping the semaglutide schedule unchanged. I’m tracking my hunger scores on a simple 0-10 scale each morning and logging my weight every Friday.

2 pounds on the scale. I’ve noticed a bit more stomach rumbling around lunch, but no diarrhea or headaches. My resting heart rate hasn’t shifted, and my HRV looks stable compared to baseline.

I’m planning to keep this going for another two weeks then reassess, maybe bump the amlexanox to 75 mg if tolerated. Just sharing what I’m seeing; definitely not proof of anything. Would love to hear if anyone else has tried stacking something like this with a GLP-1.

Comments

• tiredmira: 5 mg weekly plus 30 mg amlexanox with breakfast and dinner. For me the hunger scores dropped a point or two after the first week, but the effect faded by week three and I didn’t see extra weight loss beyond what the semaglutide was already doing. I also noticed a bit more gurgling in my gut after lunch, nothing painful though. Basically it felt like a mild, short‑lived appetite tweak rather than a game changer. Have you checked your fasting glucose or insulin trends? Curious if any metabolic ma

Community discussion - research and educational context only. Not medical advice.