Semaglutide titration notes: appetite shifts and sleep trends

Posted by weekendnate in Weight Loss & Metabolic - 1 points, 3 comments.

5 mg. I kept a simple food log and rated hunger on a 1-10 scale before meals. 5 mg I noticed a modest drop in evening snacking, maybe a 2-point reduction in hunger scores.

0 mg the urge to nibble after dinner faded pretty consistently, though I still got hungry if I skipped lunch. 0 mg injection and occasional loose stools that resolved within a day. I tracked my HRV overnight with a wearable and saw a small dip of about 3 ms the night after each dose increase, returning to baseline by the second night. 5 mg step.

Comments

• tiredmira: 25 mg to 1 mg over four weeks and noticed a similar pattern. 5 mg mark my evening cravings dropped about two points on my hunger scale, and I slept a bit lighter the night after each increase – my Oura showed HRV down roughly 2‑4 ms, back to normal by day two. I also got mild GI upset that cleared quickly. Have you tracked any changes in resting heart rate or body temperature alongside the HRV dip?
• jared467: I didn’t log resting heart rate or temperature, just HRV and hunger. Anecdotally, I felt a tiny bump in pulse the night after dosing but nothing I could measure reliably. 😅
• weekendnate: I also noticed a faint pulse rise after each increase, usually around 2 bpm higher on my nightly check, but it faded by morning. Did you try logging resting HR to see if it lines up with the HRV dip?

Community discussion - research and educational context only. Not medical advice.