Retatrutide titration log – appetite, sleep and HRV notes

Posted by weekendnate in Weight Loss & Metabolic - 2 points, 0 comments.

I started retatrutide at 1 mg once weekly last Monday, planning to bump up by 1 mg every week until I hit a dose that curbs appetite without wrecking my gut. Day three I noticed a dull nausea that faded by evening, and my usual evening snack cravings dropped about half. Sleep felt a bit lighter – I woke up once around 3 am but fell back asleep fast, and my HRV stayed steady around 62 ms (baseline is 58‑65).

No noticeable heart‑rate jump yet, but I’ll keep an eye on it as the dose climbs. 2 lb after four days, which is mostly water I guess. Anyone else mixing this with resistance training and seeing changes in recovery or energy expenditure? Would love to compare notes on titration speed and side‑effect patterns.

Community discussion - research and educational context only. Not medical advice.