Trying spermidine daily for 4 weeks – any changes in energy or skin?

Posted by elle_z in Longevity & Anti-Aging - 2 points, 0 comments.

I decided to give spermidine a go after reading about its autophagy‑inducing properties. I started with 2 mg first thing in the morning with water, just like the label says. Week one felt pretty normal, no noticeable shift in my energy levels or sleep.

By week two I began to feel a bit lighter in the mornings, like I woke up without that usual grogginess leh. My skin also seemed a tad smoother, especially around the forehead, though I’m not sure if that’s just the extra hydration I’ve been drinking. Week three brought a subtle boost in focus during my freelance writing sessions, I could stay on task a bit longer before needing a break.

Now in week four the effects feel steady but not dramatic – nothing shiok, just a gentle sense of better recovery after my evening walks. I’m curious if anyone else has tried a similar dose and noticed changes in biomarkers like fasting glucose or inflammation markers. Would love to hear your logs or any tweaks you’d suggest for the next cycle.

Community discussion - research and educational context only. Not medical advice.