ResearchSafe

Anyone tried topical LL-37 on trail rash or road rash?

Posted by grinder265 in Healing & Recovery - 1 points, 2 comments.

Hey folks, I got a pretty nasty abrasion on my shin from a technical trail run last week – think deep gravel rash that kept opening up when I flexed. I’ve been using oral BPC-157 (500 mcg twice a day) for general recovery but wanted to see if something topical could speed up the skin side. I sprayed a dilute LL-37 solution (about 50 mcg per spray) on the cleaned wound twice daily, letting it air dry before putting on a light breathable bandage.

For me, the redness seemed to calm down a bit faster than usual and the scab formed a day earlier than with just cleaning and bandaging alone. I did notice a mild sting right after spraying and a tiny bit of local redness that faded after an hour – nothing that made me stop. Has anyone else tried LL-37 on similar outdoor injuries?

Did you see a noticeable difference in healing time or any irritation that lingered? Curious about dosing frequency too – is twice a day overkill or just right? Ngl would love to hear what’s worked for you all.

Comments

  • tiredmira: I tried something similar on a scraped knee from a mountain bike fall – I used a very dilute LL-37 spray (about 20 mcg per puff) three times a day after cleaning. For me the sting was pretty mild and gone in a few minutes, and the scab seemed to harden a bit sooner than with just a plain saline rinse. I didn’t track exact healing days, but the wound looked less angry after 48 hours. 😅 I’m curious if anyone noticed a difference in scar thickness or if the irritation ever built up with more freq
  • grinder265: I kept a simple log – redness peaked around hour two then dropped to baseline by hour four each day, no cumulative irritation after five days. My scab hardened noticeably by day three versus day five with just saline. Did you notice any difference in scar flexibility after a week or two? Curious if the peptide affects collagen laying down.

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