Injection site irritation and unexpected heart rate spikes with SLU-PP-332

Posted by casey613 in Safety & Side Effects - 2 points, 0 comments.

I’ve been running a low‑dose SLU‑PP‑332 protocol for about six weeks now, mostly 5 mg every other day subcutaneously in the abdomen because the oral form isn’t available locally, and I’ve noticed two things that gave me pause. First, after each injection the site turns a bit red and feels slightly tender for a few hours, more than the usual pin‑prick soreness I get with BPC‑157, and on the third or fourth dose the redness seemed to linger longer, almost like a mild dermatitis that fades after a day. I tried rotating spots and using a tiny amount of sterile saline to flush the needle, which helped a little but didn’t fully stop the irritation.

Second, I’ve been tracking my resting heart rate and, surprisingly, it creeps up by 5‑7 beats per minute on the days I inject, even though I don’t feel any palpitations or anxiety. I haven’t changed any other supplements or training load, so I’m wondering if the ERR activation could be affecting autonomic tone or if it’s just a coincidence. Has anyone else seen similar injection‑site or heart‑rate effects, and are there any tweaks (different site, slower injection, lower dose) that seemed to mitigate them? Any lab work suggestions to monitor safety would also be appreciated.

Community discussion - research and educational context only. Not medical advice.