My first 8‑week titration with Survodutide – appetite drop and a strange energy dip

Posted by wes_cycles in Weight Loss & Metabolic - 1 points, 0 comments.

I started Survodutide about two months ago after reading up on the dual GLP‑1/glucagon profile and thought the weekly injection would fit my schedule better than daily semaglutide. I began at 0.6 mg on week 1, felt a mild nausea on day 2 that settled after a night of extra water, and noticed my appetite was already down by roughly 30 % – I could skip my usual 300 kcal snack without feeling jittery.

From week 3 I upped to 1.2 mg and tracked my HRV; it dipped a bit for the first three nights (maybe the glucagon‑induced hepatic fat oxidation), but by day 5 it was back to baseline and my resting energy expenditure on the wearable seemed a touch higher. Weight loss was 1.8 kg over the first four weeks, mostly water and a little fat.

At week 6 I hit 2 mg and started feeling a low‑grade fatigue in the afternoons that wasn’t there before – I logged it as “energy dip” and added a short walk after lunch, which seemed to help. No diarrhea or constipation yet, just occasional mild constipation that cleared with a bit more fiber.

I’m curious if anyone else has felt that mid‑day slump when the dose passes the 2 mg mark, and how you manage it – more carbs, extra electrolytes, or just ride it out?

Community discussion - research and educational context only. Not medical advice.