Ipamorelin + tesamorelin before bed – any real sleep data or just placebo?

Posted by fasted_scientist in GH & Growth Peptides - 5 points, 0 comments.

5 mg) with ipamorelin (250 mcg) each night for about three weeks now. I’m an ICU nurse so my sleep is already fragmented, but I’ve noticed I wake up feeling less groggy and my Oura ring shows a bit more deep sleep – maybe 10‑15% up from baseline. I also get a mild hunger pang around 2 am, which fits the ipamorelin profile.

I’m keen to know if anyone else has tracked objective markers like HRV or sleep stages with this combo, or if the improvement could just be placebo from expecting better rest. The knowledge base says the pair gives a synergistic GH pulse, but I haven’t seen any human studies on sleep quality specifically. Does anyone have links to trials or personal logs that show a clear effect beyond subjective feeling? Would love to see some data before I decide whether to keep stacking or just stick with ipamorelin alone.

Community discussion - research and educational context only. Not medical advice.