ResearchSafe

SLU-PP-332 cycled alongside my KLOW, worth the stack overlap or too much?

Posted by grinder265 in Protocols & Stacks - 2 points, 3 comments.

Been digging into SLU-PP-332 since the exercise mimetic stuff caught my eye. Ngl the animal data on fat oxidation without appetite change is interesting for someone who logs a ton of miles and watches body comp.

My question is more about layering than dosing since human dosing isnt even established yet. If I keep running my KLOW (BPC/TB/GHK/KPV daily with TB and GHK 2-3x per week) for an achilles thats still grumpy, and add SLU-PP cycled say 4 weeks on 4 weeks off on top, is there any reason to worry about overlap? TB-500 already does some metabolic and inflammatory stuff, KPV is hitting NF-kB, and now wed be pushing mitochondrial biogenesis on top of all that recovery signaling.

For anyone whos run both, did you keep KLOW going through the SLU cycle or pause the TB-500 and GHK-Cu to keep things cleaner? Also curious if morning fasted vs post run changes anything for the ERR agonist timing.

Comments

  • luis_t: Honestly I never ran the SLU compound, but a thought on overlap since you're already juggling a lot of signaling. With TB-500 and GHK-Cu still in the mix, the recovery and inflammatory angles are already covered pretty well, so the case for keeping them going purely for support during an SLU cycle is weaker than just running the mimetic on its own and seeing what it actually does for you. For me, cleaner read-outs matter when something is new, no? If you're trying to figure out if SLU is doing
  • grinder265: Yeah thats fair, i kinda had the same gut feeling when i typed it out. Ngl the "cleaner read" angle is what got me posting this in the first place, because if im gonna bother cycling SLU at all i wanna actually know if its doing something. My only pushback is the achilles is still temperamental at like 12 weeks post flare, so going cold turkey on TB-500 feels like bad timing. Would you keep just BPC + KPV daily through the SLU cycle and drop TB/GHK, or is that still too much overlap on the infl
  • quiet_ironman: Yeah that makes sense, cleaner read-outs are kinda the whole point when something is unproven in humans. I kinda do the same thing when I'm trying something new, drop what isn't necessary so I'm not guessing which thing did what. Have you ever had a tendon that just refused to fully calm down though? That's the part that makes me hesitate, achilles stuff can linger and I'd hate to lose ground by pausing TB/GHK for the cycle window.
  • grinder265: Yeah that's my exact worry tbh. The achilles is month 6 now, was pretty locked up at month 4 before i started KLOW and it did calm down a lot but its still not 100%. Dropping TB for 4 weeks while i run SLU feels like the kind of thing where i'd lose progress and not even know if it was worth it. Leaning toward keeping TB in at 2x/wk through the cycle and only pausing GHK, since KPV is daily and doesnt really overlap with what SLU is doing anyway.

Community discussion - research and educational context only. Not medical advice.