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GlyNAC + topical diclofenac during a cut, anyone running this together?

Posted by noor_zone2 in Protocols & Stacks - 2 points, 4 comments.

So I've been tinkering with my spring recomp and I added a couple of things I don't usually run. GlyNAC in the morning with breakfast, glycine and NAC each at about 100 mg per kg split into two doses, and diclofenac gel on cranky joints after heavy squat sessions. I figured the GlyNAC would help with the oxidative load from training in a deficit, and the topical NSAID keeps me moving without touching my stomach.

Two weeks in and my recovery feels smoother than usual, soreness drops off faster and my elbows are way less grumpy. Could be placebo, could be the better sleep, hard to say. The NAC taste is real, sulfur city, I chase it with orange juice. I do worry about zinc and copper depletion long term so I added a multimineral.

Has anyone here stacked GlyNAC with a topical anti inflammatory during a cut? Curious if you noticed the same recovery bump or if it flattened out. Also wondering whether morning vs post workout NAC matters much, fwiw the half life is around 6 hours so timing both ends of the day made sense to me.

Comments

  • restless_reads: Cool stack honestly. I ran GlyNAC by itself for about 8 weeks last fall, glycine and NAC both at 1g each twice a day, and honestly the biggest thing I noticed was sleep, I was out cold and waking up way less during the night. Recovery felt a bit smoother too but could totally be the sleep thing, hard to untangle. I never combined it with topical diclofenac though. Curious why you picked diclofenac gel over something like a CBD salve, was it a specific joint thing or just what you had on hand? T
  • noor_zone2: Yeah the sleep thing is real, I noticed that too, like week 2 I was sleeping harder and waking up less. Funny you say 1g twice daily, I actually titrated up to that same number on each, glycine and NAC, took me a couple weeks to get there without my stomach getting weird from the NAC. Diclofenac was just what my ortho had samples of after a flare up in my left elbow, not a philosophical choice lol. The CBD salve angle is interesting though, I tried one before and it felt more like a nice lotion
  • luis295: Glycine and NAC both at 1g twice a day is pretty much what I run too, fwiw, and the sleep effect was the first thing I noticed. The cut just amplifies it for me. On the diclofenac question, for me it was specifically tendon stuff in the elbows, NSAIDs actually have decent data for superficial tendon irritation topically and it seemed to help more than a CBD salve did, but ymmv. What was the rest of your post, got cut off?
  • noor_zone2: Yeah the post got cut off, I was gonna ask about timing the diclofenac relative to training, like do you put it on right after or wait a bit? I've been doing it maybe 30 min post-session. Interesting you had the same elbow thing, mine is the medial side, feels like it's the tendon not the joint itself. The sleep bump surprised me too, I wasn't expecting that from GlyNAC but it's been pretty consistent. Fwiw I tried a CBD roll before the diclofenac and it did nothing for me either.

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