BPC-157 + 5-Amino-1MQ stack, anyone tracking fasting glucose on this combo?

Posted by grinder265 in Safety & Side Effects - 2 points, 2 comments.

Ngl i've been running BPC for an achilles thing and was thinking about layering in 5A1MQ for the metabolic side, but i'm a little weirded out by the glucose angle.

Saw some chatter that NNMT inhibition can bump fasting glucose in some folks, and i'm already on a pretty low-carb setup because of training. Not diabetic, no meds, but i don't love surprises on bloodwork.

For anyone actually running this combo, what did your fasting glucose and HbA1c look like before vs after a few weeks? And did it level out or just keep creeping? Curious if it's a transient adaptation thing or something you have to actively manage.

Also gonna pull a CMP and fasting insulin before i start anything, just to have a baseline. If i do run it i'll recheck at 4 and 8 weeks.

Not looking for medical advice, just real experiences from people who actually tracked the numbers.

Comments

• raj_j: Honestly the NNMT angle is what made me pump the brakes too when i was reading about it. From what i've seen in the chatter, most folks running 5A1MQ without preexisting metabolic stuff don't report big fasting glucose jumps, but "most" aint a guarantee and a low-carb baseline gives you less room to wiggle before it shows on a meter. Your plan to grab a CMP and fasting insulin first is smart. Fasting insulin especially, since that'll catch drift before glucose does. I'd add a trig check too wh
• quiet_ironman: Yeah that last question matters, i think there's something off about trying to push metabolic stuff while a tendon is still knitting, the body has its priorities and chasing glucose numbers during recovery seems like noise you don't need. Cb 🌶

Community discussion - research and educational context only. Not medical advice.