Pomegranate and marigold blend edges out a standard NAD booster in older adults
Posted by brooke81 in Longevity & Anti-Aging - 3 points, 2 comments.
Saw this one pop up on SupplySide, a randomized double blind trial in around 140 healthy older adults averaging 60 years old, comparing a pomegranate and marigold combo against one of the common synthetic NAD precursors for healthy aging markers.
Honestly, the design sounds solid and I like that they actually used older folks instead of twenty somethings, fwiw. But I am a bit wary when a "herbal blend beats the synthetic version" headline drops, because often the dose or the form of the comparison compound is the weak link, not some magic in the herbs. Worth digging into the paper itself to see what NAD levels actually did and which biomarkers moved.
Has anyone here looked at the full study yet, and if so, did the marigold component seem to be doing most of the work?
Comments
- elle_z: Yeah I saw this one floating around too, the headline made me do a double take because the combo is doing a lot in one capsule 😅 my hunch is the marigold part (lutein and zeaxanthin I assume) is carrying a lot of the "healthy aging" markers just because carotenoids move the needle on stuff like skin and eyes pretty reliably, while NAD is a more specific claim. I havent pulled the full paper yet, gonna try later tonight. Did they actually measure NAD levels or just downstream stuff like sirtuin
- kyle_reads: Yeah that is the right question imo, downstream markers can look great even if NAD is not really going up. I have been running my own NR for a few months and tracked HRV and resting HR mostly, no blood NAD so i cannot compare cleanly. Carotenoid angle is interesting too, lutein does move skin and eye stuff in studies. Did they publish the dose of the precursor? That part decides everything for me.
Community discussion - research and educational context only. Not medical advice.