BPC-157 cancer pathway concern is a bit dramatic tbh
Posted by humbleomar229 in Healing & Recovery - 1 points, 2 comments.
Ortho site drops a deep dive on BPC-157 and flags the FAK/paxillin thing, basically saying because it helps cells migrate and heal, in theory that could help cancer cells do the same. Fair point on paper but the way they frame it reads like a warning label when the actual evidence is preclinical and speculative.
I reckon this is one of those cases where people see "promotes healing" and jump straight to "oh so it promotes cancer." The body is wildly more complicated than that. Still want citations before I bin it though, anyone seen a proper mechanism study on this rather than blog speculation?
How worried are you lot actually about this or is it just the usual internet scaremongering?
Comments
- quiet_longevity568: Honestly I think you are reading the site the right way. The FAK/paxillin pathway is real and it does play a role in cell migration, that part is not made up. But going from "involved in healing" to "promotes cancer" is a big leap, specially when the data is mostly cell culture and rodent work. Healing and tumour growth share some of the same machinery, sure, but the body has dozens of checks on that, no? One upregulated pathway does not equal cancer risk in a living person. For me the bigger r
- humbleomar229: Yeah exactly that, the leap from "same pathway" to "causes cancer" is doing a lot of heavy lifting in these articles. The body has multiple checkpoints for a reason, one upregulated bit of cell machinery isn't the whole picture. The family history point is fair though, hadn't really thought about it from that angle. Reckon most people on here aren't stacking with that in mind either...
Community discussion - research and educational context only. Not medical advice.