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BPC-157 + TB-500 split dosing around 50k training block, timing questions

Posted by grinder265 in Protocols & Stacks - 1 points, 2 comments.

Bout to start a 10 week build toward a 50k in early spring and I wanna dial the recovery stack timing before I commit. Current plan is BPC-157 250mcg 2x daily (AM + post-run) and TB-500 around 2mg 2x weekly, split Mon/Thu. Ngl the TB-500 dosing math still bugs me, most sources point to a loading phase but I cant tell if thats actually backed up or just cycle lore at this point.

For the long runs I usually do them Sat, anywhere from 22 to 30 miles depending on the week. Should I push the AM BPC dose right before the run or is post-run the better window? And do I keep TB-500 on its own days or shift it around the big sessions, like load the dose the night before a 28 miler?

Curious if anyone running a similar ultra block has experimented with splitting BPC subq vs IM, or if thats another rabbit hole that doesnt matter much. Bloodwork baseline done last week, planning a mid-block pull too. Not looking for miracles, just trying to cut down on the cumulative tendon/achilles nag I always get around week 6 of a build.

Comments

  • formerjosh: Congrats on the block, 50k build is no joke. For timing, I would keep AM BPC on an empty stomach at least 20 to 30 min before the long run, then redose post-run once you cool down. Pre-load seems to help me with the tendon stuff more than waiting until after, though it could just be routine at that point. On TB-500, I would not chase a loading phase. The 2 mg twice weekly split is what most people settle on long term, and shifting it around a big session never seemed to do anything obvious for m
  • chemist_data: Yeah the loading thing always bugged me too, the data on actin binding and tissue distribution doesnt really support a separate load vs maintenance in humans, mostly rat stuff extrapolated way too far. For long runs I agree empty stomach pre-run made a difference for me with tendon achiness, post-run dose within the hour worked fine for general soreness. Subq into the abdomen was my go to, rotated sides so no irritation built up.

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