Fisetin as a senolytic, anyone actually doing the hit and run protocol?

Posted by priya_labrat in Longevity & Anti-Aging - 1 points, 0 comments.

Ngl i'm pretty new to all this longevity stuff and i've been going down a proper rabbit hole lately. Started reading about senolytics and the idea of clearing out senescent cells actually made sense to me, way more than just chasing antioxidants like i used to.

I'm eyeing fisetin as the entry point because it sounds gentler than some of the others, and the short half life means you're not on it constantly which appeals. I've been looking at the profiles on here and the 20 mg/kg hit day style protocols come up a lot. Is anyone actually running it like that? Like real hit and run, not daily?

Also a daft question maybe, but do you take it with fat to help absorption like i've seen mentioned? I keep going back and forth on whether to bother with something like this before getting proper bloodwork and a clear baseline sorted first. Keen to hear what people who've actually tried it reckon, good or bad.

Community discussion - research and educational context only. Not medical advice.