Why the max tolerated dose approach is a joke

Posted by hank698 in Protocols & Stacks - 2 points, 0 comments.

https://www.oncologynewscentral.com/oncology/cancer-drug-dosing-concerns-prompt-asco-response

this piece from asco talks about how the old way of using the maximum tolerated dose for cancer drugs might actually be harmful. it basically says we should be looking for an optimal dose instead of just pushing the limit until the patient gets sick.

not gonna lie, it is about time they caught on to this. i reckon the same logic applies to how some people run their stacks here. i have seen way too many guys just cranking the dose up until they hit a wall of side effects, thinking that more is always better. in my own experience, that is usually where the gains stop and the crashes start.

it makes me wonder if we are all just guessing too much with our own protocols. do you reckon we are overshooting the optimal dose on common peptides because we are chasing a feeling instead of actual results? i am keen to hear if anyone has found that lower doses actually worked better for their recovery.

Community discussion - research and educational context only. Not medical advice.