Trying low‑dose rapamycin – anyone else doing weekly pulses?

Posted by gina_zone2 in Longevity & Anti-Aging - 1 points, 0 comments.

Hey all, tbh I’m pretty new to the whole longevity stack and I’ve been reading about rapamycin as the “most studied” anti‑aging drug. The page says a typical low‑dose is 3‑6 mg once weekly, half‑life around 62 hours, and that it can boost autophagy and even improve vaccine response. I decided to give it a quiet try last month – started with 3 mg on a Saturday night after a light dinner, then skipped the next week to see how I felt.

For me the only thing I noticed was a slight sore spot on the inside of my cheek a day or two after the dose, which cleared up on its own. Sleep seemed a tad deeper, but maybe that was just the extra rest I took that weekend. I’m curious if anyone else has stuck with the weekly schedule, tried a different day of the week, or adjusted the dose up to 5 mg?

Also any tips on monitoring lipids or other labs while on it would be appreciated 🧬. Thanks!

Community discussion - research and educational context only. Not medical advice.