GHK-Cu review on PMC, the gene expression angle is what makes it interesting

Posted by grinder265 in Healing & Recovery - 2 points, 0 comments.

https://meto.co/blog/ghk-cu-copper-peptide-benefits

There's a 2018 review on PubMed Central that goes deep on GHK-Cu's regenerative actions, and the part that stood out to me is how much it leans on gene expression data. Roughly 4,000 genes seem to respond to this peptide, which is wild when you think about it for such a tiny molecule.

For healing work, the wound closure and collagen stuff tracks with what I've seen anecdotally, especially around skin and superficial tissue. The interesting question for me is whether injectable GHK-Cu actually does anything meaningful for deeper tendon or joint tissue, or if that effect is mostly local and surface level. The review talks a lot about skin penetration and topical use, but I don't see strong evidence it reaches a cranky Achilles or a beat-up meniscus in any real concentration.

Anyone here actually layered injectable GHK-Cu into a tendon stack and felt a difference over a BPC or TB-500 only run?

Community discussion - research and educational context only. Not medical advice.