Kisspeptin flushing and headaches, is tachyphylaxis real or am I just dosing wrong

Posted by leah_vo2max in Safety & Side Effects - 1 points, 0 comments.

Ran kisspeptin-10 subq for about 3 weeks, mostly the hpg version at like 200mcg twice a day spaced out, and the flushing thing is no joke. Like within 5 min of pinning my face and ears go red and hot for maybe 10-15 min, sometimes i get a dull headache right behind my eyes that fades on its own. To be fair the libido lift was noticeable by week 2 and my morning wood came back which i was not mad about.

But the question i actually have, the profile mentions possible tachyphylaxis with continuous use which kinda freaked me out. Has anyone run it longer than a month and seen the LH response actually drop off? I was thinking maybe cycling 5 on 2 off or only using it pre bed since the half life is so short anyway. Also curious if splitting the dose matters, like would 100mcg 4x a day be smoother than 200mcg 2x, or does it not matter given how fast it clears.

Bloods mid cycle showed LH up nicely and total T bumped about 200 points from baseline so something is working, just want to not burn out the response.

Community discussion - research and educational context only. Not medical advice.