ResearchSafe

oxandrolone bloodwork - hdl drop at 10mg daily

Posted by amber464 in Safety & Side Effects - 2 points, 4 comments.

been running oxandrolone 10mg split dose for six weeks now mostly for recomp while cutting. got my mid-cycle bloods back yesterday and my HDL crashed to 28 from a baseline of 46, which is a pretty substantial hit for such a low dose. LDL crept up a bit too but not as dramatically. liver values are actually fine, ALT and AST barely moved, so that's the one bright spot. honestly didn't expect the lipid profile to get wrecked this hard at 10mg, makes me think I'm just sensitive to it or maybe the split dosing keeps it in my system longer. probably going to drop it this week and run some NAC and niacin to try to bring HDL back up before I even think about touching another oral.

Comments

  • biohacker_cora: tobe fair i have seen similar drops on low dose orals and it usually comes back fast once you stop but six weeks is not nothing and hdl can be stubborn to recover i ran var at 5mg for eight weeks a while back and my hdl went from 62 to 41 and took about ten weeks post cycle to get back to baseline but everyone responds different and lipids are so individual to be fair what were your other numbers like ldl trigs total cholesterol and did you run any support like niacin or berberine or just let it
  • amber464: thanks for the context cora. my ldl went 98 to 134 trigs 72 to 89 total 185 to 212. ran tudca nac and 500mg berberine daily but no niacin cause flushing sucks imo. next panel scheduled week eight so two weeks out. curious if the berberine blunted the ldl spike at all or if it woulda been worse without it. your ten week recovery tracks with what ive seen in lab data too.
  • aspiring_codes: berberine has some data for modest ldl lowering but hard to isolate effect without a control panel 👀 from what ive seen clinically the lipid hit from low dose oxandrolone tends to reverse within 8 to 12 weeks after stopping especially if baseline was decent glad liver markers held steady that tracks with most n of 1 reports at this dose range worth retesting at week ten off cycle to confirm trend ❓
  • amber464: berberine crossed my mind but ive seen mixed lipid panels on it so im holding off until i see where things settle naturally. the 8 to 12 week reversal window matches what ive read too so that lines up. liver holding steady was the main reason i even ran it this long imo. planning to retest at week 8 off then again at week 12 to catch the trend. you think berberine 500mg bid would be worth adding at the 4 week mark or just let it ride?

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