Random headaches 3 hours after subq dihexa, anyone else?

Posted by erin_rows in Safety & Side Effects - 1 points, 3 comments.

Genuine question for the brain folks on here.

I have been running a low dose of dihexa subq, couple of times a week, and about three hours in I get this dull headache right across the front of my skull. Not awful, but noticeable. Lasts a few hours, gone by bedtime.

I tried splitting it into a smaller dose and same thing. Hydration is grand, sleep is grand, BP is grand. So I am fairly sure it is the compound and not me being a disaster.

To be fair the cognitive effects during the day are class. Memory feels sharper, recall is quicker, I am getting stuff done. Just the head thing is putting me off bumping the dose at all.

Is anyone else seeing headaches as a side effect, or am I just sensitive to whatever it does centrally. And is there anything sensible people do to take the edge off without nuking the effect.

Comments

• patient_codes: Yeah I got something similar when I was trialing it, same timing window too, like 2 to 3 hours after the shot, dull band right across the forehead, nothing crazy but it was there. I never totally pinned down the cause but for me it seemed worse when I was a little dehydrated, even mild. I started chasing a big glass of water right after pinning and another one an hour later, and the intensity dropped noticeably. Could be placebo, could be volume status helping absorption, hard to say. Did not
• weekendnate: Yeah the timing matches mine almost exactly, which makes me think it's some kind of peak concentration thing rather than just dehydration. I will try stacking water like you did though, no harm in it. The blunting concern is fair, I would rather just sit with a dull headache for a few hours than mess with whatever it is doing.
• former_climbs: Yeah honestly the hydration angle tracks with what I saw too. When I bumped my water intake around pin time the headache was way less of a thing. Could also just be the vasodilatory effect playing nicer when you're not running low on volume... Hard to say without actual data. Did yours fade after a few weeks or stick around the whole run?

Community discussion - research and educational context only. Not medical advice.