Anyone running tesamorelin alongside a GLP-1, worried about the muscle loss angle?

Posted by grinder265 in Protocols & Stacks - 1 points, 0 comments.

Been digging into the apollo stack concept and the thing thats nagging me is the muscle preservation question. Sema or tirz on its own already has that risk for endurance athletes like myself, add in aggressive caloric deficit and you can really eat into lean tissue if youre not careful. Tesamorelin supposedly helps with visceral fat specifically but its still GH mediated, so im not sure how that balances out.

Curious if anyone here has actually stacked a GLP-1 with tesa and tracked body comp over time. Dexa or inbody data would be ideal but ill take subjective reports too. Ngl im mainly wondering if the tesa offsets the muscle loss or if its just adding another variable to manage.

My training volume is high so im not super worried but i also dont want to come out of a cut looking flat. Whats been peoples experience, specifically on the strength and recovery side while running something like this. Also open to hearing what people are doing for protein intake and timing around the GLP-1 shot day since appetite is basically gone.

Community discussion - research and educational context only. Not medical advice.