CagriSema week 4, glucose numbers look weird, is this a thing?

Posted by tiredmira in Weight Loss & Metabolic - 1 points, 0 comments.

Started CagriSema about a month ago and my fasting glucose actually went up the first two weeks before dropping.

I had a CGM on so I watched it in real time and it was kinda frustrating. My fasting numbers were sitting around 95 to 102 for like 10 days, then suddenly started trending down into the high 80s by week 3.

I am eating less obviously so I figured it would just drop, but the early bump surprised me. HRV also dipped the first 10 days and sleep felt rougher too, both have come back to my baseline now.

Has anyone else seen glucose briefly rise before it falls on CagriSema? I get that the amylin piece is doing its own thing alongside the GLP-1 part, so maybe that is just the dual pathway settling in. Just curious if this matches what others have tracked or if I am reading way too much into two weeks of data 😅

Community discussion - research and educational context only. Not medical advice.