BPC-157 oral + LL-37 for a slow-healing surgical wound, anyone run this?

Posted by tracker_jade in Healing & Recovery - 1 points, 1 comments.

Had a minor procedure about 6 weeks ago and the incision site is healing, but way slower than my provider expected. No signs of infection, just kind of stuck in that angry red phase.

I already use BPC-157 oral, around 500 mcg once a day, and it has helped a lot with the deeper tissue stuff anecdotally. But the surface of the wound just seems to be dragging.

I have been reading about LL-37 and its role in re-epithelialization and wound closure. The antimicrobial angle is interesting too since I am paranoid about the site getting messed up at the gym.

Has anyone actually stacked oral BPC with topical or systemic LL-37 for a stubborn post-surgical wound? Curious if the mechanisms overlap too much or if they actually complement each other. Also wondering if timing matters, like does LL-37 need to be applied at a specific stage of healing to do anything useful.

Comments

• recovery_theo: Honestly I'd loop your provider back in before adding anything new, because 6 weeks stalled at angry red is worth them actually looking at again (not trying to be preachy, just wouldn't want you stacking things on a wound that might need a different approach). On the mechanistic side, from what I've read the BPC and LL-37 pathways do seem more complementary than redundant. BPC tends to get talked about more for the angiogenic and tendon/soft tissue stuff, while LL-37's case (re-epithelializatio
• priya_fasted: Yeah fair point on looping the provider back in, i keep meaning to and then i dont. The red isnt getting worse just not budging, but still probably worth the call. The surface vs deeper layer split between LL-37 and BPC actually makes a lot of sense when you put it that way.

Community discussion - research and educational context only. Not medical advice.