CagriSema week 2 and I'm weirdly hungry, is this the loading phase being aggressive?

Posted by tiredmira in Weight Loss & Metabolic - 1 points, 0 comments.

Started CagriSema about two weeks ago and I was fully expecting the appetite to vanish by now based on what I read on the CagriSema profile here (cagrilintide + semaglutide combo, dual appetite pathway stuff).

Instead I'm sitting around the same hunger level as before, maybe a touch lower on food noise but nothing dramatic. I'm tracking calories and my intake has barely budged.

For context I titrated up fast because my prescriber wanted me at the full 2.4/2.4 by week 4. So I'm basically at 1.0/1.0 right now and still eating like normal.

Is the cagrilintide component just slow to kick in compared to the semaglutide side? Or did I basically waste the loading window by going up too fast before the amylin effect had time to settle in 😅

Curious if anyone else had a flat first two weeks before it actually turned the corner. My weight on the scale is doing nothing and it's making me twitchy.

Community discussion - research and educational context only. Not medical advice.