Mayo Clinic senolytic combo shows promise for diabetic kidney damage
Posted by megan_t in Longevity & Anti-Aging - 1 points, 0 comments.
Mayo Clinic just put out findings that a senolytic combo (dasatinib plus quercetin) reduced the effects of those so-called zombie cells in diabetic kidney disease. They are saying it could help slow or even halt kidney damage in diabetics, and that larger trials should be next.
Not gonna lie, this one caught my eye because diabetic kidney stuff is a huge deal and most of what I see on senolytics is either super early mouse work or hype about looking younger. Actually seeing a named clinic with a real patient population look at organ outcomes is a step up.
My question is whether D plus Q at the doses they used would even move the needle for general longevity stuff outside of kidney disease, or if the benefit is really specific to that tissue. Has anyone here looked into whether these results translate at all into the healthy aging crowd, or is this firmly a disease-treatment story for now?
Community discussion - research and educational context only. Not medical advice.