Anyone else notice nausea spikes after upping compounded tirzepatide dose?

Posted by tracker_jade in Safety & Side Effects - 1 points, 0 comments.

5 mg weekly for weight management and felt fine for the first few weeks, just a bit less appetite and some mild fatigue. When my clinic bumped me to 5 mg, the nausea hit harder about a day after the injection. It wasn’t just queasy stomach; I actually threw up once and had loose stools the next day.

75 mg and the GI upset eased within a couple of days, though I still notice a dip in appetite that lasts longer than before. I’ve been keeping a simple log of timing, food intake, and how I feel, and it looks like the side effects line up with the peak concentration window (around 24‑36 hours post‑shot). Has anyone else seen a similar pattern when titrating up? I’m planning to get basic labs next month to check electrolytes and liver just to be safe, but I’m curious if others have found a dose‑splitting schedule or anti‑nausea tricks that helped without losing the weight‑loss benefit.

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