First week on CagriSema, appetite, nausea and weight tracking notes

Posted by amber464 in Weight Loss & Metabolic - 0 points, 0 comments.

4mg split once a week subQ in the thigh. Imo the appetite drop hit hard by day three, I barely finished my usual lunch and snacks felt pointless. 2lb drop by day five, mostly water I think.

HRV on my overnight strap showed a small dip the first two nights then crept back up by night four, which I took as a sign my body was adjusting to the lower intake. Nausea showed up in the evenings around hour 12 post injection, mild but enough to make me skip my post‑workout shake. I kept my usual lifting routine three times a week and didn’t notice any strength loss yet.

Imo the combo feels stronger than sema alone for curbing cravings, but the GI side is noticeable. Gonna keep logging weight, food intake and HRV for another two weeks before deciding whether to stay at this dose or taper down. Would love to hear if others saw a similar early HRV pattern with CagriSema.

Community discussion - research and educational context only. Not medical advice.