Oxandrolone and HDL drop – has anyone seen bloodwork changes?

Posted by kenji_runs in Safety & Side Effects - 1 points, 0 comments.

I ran a low dose oxandrolone cycle about 8 weeks ago just to see if it’d help with strength while cutting. I split 15mg twice a day, kept my diet clean and trained hard. After the cycle i did a full lipid panel and my HDL had dropped from 58 to 42 mg/dl, LDL went up a bit too.

I felt fine otherwise, no liver symptoms or mood changes. Honestly i’m wondering if this is typical for the dose i used or if i’m an outlier. Has anyone else tracked their lipids on var and noticed similar shifts?

I’ve read that oxandrolone doesn’t aromatize but can still mess with cholesterol, but i’d love to see real world numbers or any studies that look at HDL changes with doses under 20mg daily. Also, does anyone supplement with anything like niacin or omega‑3 to offset the drop while on cycle?

Community discussion - research and educational context only. Not medical advice.