Trying PE 22-28 for mood, any logs?

Posted by coastal_labrat in Cognitive & Nootropic - 1 points, 0 comments.

Hey folks, I decided to give PE 22-28 a shot after reading about its TREK-1 blockade and fast antidepressant angle in animal models. I am not a doctor, just sharing my own tbh experience. I started with a very low dose, maybe 100 mcg intranasal once a day, because I have no human data to go on.

First three days I felt nothing special, just a bit of mild headache in the afternoon. On day four I noticed my mood felt a little lighter during my night shift, less irritable after tough calls. Tbh I also felt a bit more mentally clear when I had to write reports, but could be placebo or just better sleep from being less stressed.

I kept a simple log, rating mood 1-10 each evening, and saw a small bump from 5 to 6-7 after day five. I stopped after ten days because I wanted to see if any effect lingered, and after stopping I returned to baseline within two days. If I try again I would maybe split dose twice daily and track sleep more closely.

Anyone else tried this peptide for mood or neurogenesis? Would love to hear your logs or thoughts on dosing.

Community discussion - research and educational context only. Not medical advice.