ResearchSafe

Scalp irritation after switching to 100 mg/mL RU‑58841, any tips?

Posted by liam_sleepnerd in Safety & Side Effects - 1 points, 0 comments.

1 mL to the crown each morning. The first three weeks were smooth, I saw a bit of density improvement and no systemic changes, which was reassuring. Around week four I started noticing a mild itching and some dry flakes exactly where I’d been spraying.

I tried diluting the vehicle to 70 mg/mL and adding a few drops of aloe gel, but the irritation persisted, though it felt a little less harsh. My HRV and sleep stayed steady, but I did see a slight dip in my morning cortisol on the day after the itch flared. I’m wondering if anyone has found a better solvent blend or an anti‑inflammatory add‑on that doesn’t interfere with the anti‑androgen activity.

Also, any thoughts on whether a lower frequency (every other day) might keep the scalp happier while still getting results? Appreciate any practical advice.

Community discussion - research and educational context only. Not medical advice.