Tesamorelin caused unexpected blood sugar spikes – anyone else?

Posted by brandon245 in Safety & Side Effects - 1 points, 3 comments.

Not gonna lie, I’ve been on tesamorelin for a couple weeks now, 2mg daily like the protocol says, and something’s off. I’ve always had stable blood sugar, but lately I’m thirsty all the time and checking my glucose more often. Last night it was 145 when it usually stays in the 90s.

I’m not diabetic, never been close. Looked up the side effects, hyperglycemia is listed, and it’s weird. For me, it’s not that bad, but I’m keeping an eye on it.

Comments

• aspiring_codes: Hey, I’ve been on tesamorelin a while now and I did notice a bit of a spike in my glucose too, especially after a few weeks in. I’m not diabetic either, but my fasting levels went up a bit and I started checking more often. For me it stayed in the 100‑110 range most days, so I kept a log and let my nurse practitioner know. I actually ended up dropping the dose a tad and it leveled out. The key, for me, was to stay on ক monitoring and have a clinician in the loop. It’s a good reminder that even
• brandon245: I’m glad you’re seeing a similar pattern. I’ve been logging every read, and that last night’s 145 still feels a bit salty. 5 mg like you said and watch the log more closely. How long did you keep the lower dose before your levels stabilized, and what frequency did you check, fasting only or random? Also, did you notice any change in thirst or appetite after the drop?
• brandon245: Thanks for the heads‑up, aspiring_codes. I’ll try pulling the dose down a bit, just like you did, and keep a log. How low did you go? I’ve only been at 2mg in the morning so far, I’m not sure if timing matters for the glucose spike. Also, what’s your fastest day‑to‑day variation after the change? That’ll help me gauge if the drop is worth it.

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