ResearchSafe

Tbh new nattokinase study shows blood pressure drop – worth it?

Posted by hank_m in Research & News - 5 points, 4 comments.

I came across a 12‑week double‑blind trial that had 60 people with mild hypertension. They took 2000‑4000 FU daily on an empty stomach and the average systolic drop was about 7 mmHg. That’s a pretty noticeable change for someone like me who’s been hovering at the lower end of the scale and hasn’t seen such a drop from a natural supplement before.

The authors also noted lower blood viscosity and a reduced risk of DVT, which caught my eye because I recently had a knee injury and have been dealing with bruising. While the hype around it being a “blood thinner” feels a bit exaggerated, especially for folks who don’t need anticoagulants, the data makes me tempted to add it to my routine. Has anyone else tried it? I’d love to hear if you’ve noticed any changes in bleeding tendencies or how quickly you recover after exercise.

Comments

  • aspiring_trailrun: I’ve been on nattokinase for about six months at 2000 FU in the morning, and I’ve not seen any obvious increase in bleeding or bruising. My skin still heals normally after a light hike and I didn’t notice any excess soreness when I hit 4 × 10 km runs. That said, I keep my doses lower because I’m on an ACE‑inhibitor for blood pressure, so the combination might be a bit stronger than a single agent. Have anyone else paired it with other cardio‑supportive supplements, or seen a difference in recove
  • hank_m: Thanks for the update, i’ve also stuck to 2000‑4000 FU but on a fasted morning and have only seen my systolic dip about 7 mmHg after 12 weeks, so i’m on the same end of the scale. I’m curious: what cardio‑supportive stack have you added, maybe L‑arginine, fish oil or a low‑dose aspirin? I’ve been comparing recovery time between runs with and without nattokinase, and any metrics you track (heart rate, perceived soreness) would be great to hear.
  • greg208: I’ve tried mixing nattokinase with omega‑3 and a splash of beetroot juice a few times. No huge change to recovery, but I did feel a bit less stiffness after the long runs – probably the beetroot helped a tad. Have you tried any other blood‑flow boosters, like magnesium or L‑arginine?
  • hank_m: Tbh i’ve only mixed nattokinase with omega‑3 so far, so i haven’t seen the beetroot effect, but i did notice some extra soreness after the knee recovery runs so it sounds useful. I’ve been taking magnesium for sleep but haven’t added it to the blood‑flow stack yet, will try it next week and see if it eases the stiffness further. Any thoughts on timing?

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