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Tried a week of daily spermidine, what changed for me

Posted by greg208 in Longevity & Anti-Aging - 4 points, 3 comments.

Not gonna lie, this is my first time with spermidine and I'm a bit of a sceptic, but I thought it was worth a go after seeing the headlines about autophagy and heart health. I took 5 mg by mouth each day after dinner, the usual dose people seem happy with. The first couple of days I felt a little bloated, a touch of gut upset – mild, not a big deal – but by day four I started noticing a subtle lift in my energy at the endSimpler.

I woke up a tad easier, my sleep has felt less fragmentary, and for the first time in months I didn't feelakana that post-workout slump that usually hits me after lifting. My skin also looks less dull. I took a photo of my face last night with the same lighting and I can see a faint improvement in that tired look. I’m still tracking"fmt" but if anyone else’s experience is similar or if you’ve got tips to minimise that mild tummy upset let me know.

Comments

  • liam_sleepnerd: Tbh I was a bit skeptical before I started spermidine too, so I kept a small log, time of day, energy notes, heart‑rate variability, and a quick skin photo each week. Within a week I noticed a similar lift in post‑lift energy and a smoother sleep cycle, and HRV did trend up a few points on the average. The bloating is a common first‑stop reaction; I found spreading the 5 mg over two smaller puffs after dinner helped my gut a bit. Anyone else notice a change in skin texture or daytime focus?
  • greg208: Good to hear the lift in energy and sleep was a repeat for you. I’m also seeing a modest HRV bump – my averages are around 58‑60ms, so a few points would be noticeable. The split‑dose idea sounds smart; I’ll try two 2.5 mg sips after dinner next week. Do you notice any skin texture change beyond the dullness?
  • greg208: Not gonna lie, tracking it like that makes sense, reckon I’ll start jotting notes next time. Bloating’s a bugger, but splitting the dose might help. Did your skin texture change feel permanent or temporary?

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