RU-58841 scalp irritation – how to minimise it?

Posted by greg208 in Safety & Side Effects - 1 points, 0 comments.

I started RU‑58841 a few months ago to try and stop the hair thinning that’s been creeping up. I followed the usual 50‑100 mg dose in a 1 ml vehicle, applied it twice a day to the scalp. The first week I felt a sharp itch and a little burning sensation that made me question if I’d gotten the wrong product.

By the third week the itching had become a constant tickle, the scalp felt dry and a few tiny red bumps popped up – clear signs of contact dermatitis. I stopped using it for a week and noticed the irritation ease a lot. When I resumed, I tried mixing the cream with a mild, fragrance‑free moisturizer and also added a small amount of 4 % hydrocortisone cream on the most irritated spots during the night.

That seemed to cut the itching in half. I also made a small patch test each new batch of product before full application – a few drops on the inner wrist, wait 24 h, and if there’s no reaction, it’s probably safe for the scalp. I’ve not seen any serious side effects yet and the hair growth looks slightly better, but I’m still learning about the long‑term safety.

Anyone else have experience with scalp irritation from RU‑58841? What skincare routine helped you?

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