Did coq10 lower my warfarin level? A quick note

Posted by calm_nomad in Safety & Side Effects - 2 points, 0 comments.

I’ve been taking coq10 (about 200 mg of ubiquinol) daily for a year now because i like the idea of a heart‑supportdummy that also gives me a mild lift in energy. A few months ago i had to start warfarin for atrial fibrillation. After a few weeks of coq10, i checked my INR and it was a few points lower than the therapeutic range i usually hit. I didn’t jump to conclusions, so i ran a few more tests and my INR was consistently a bit on the low side – not a huge drop, but enough to notice.

I’m not saying coq10 causes this in everyone, but the literature notes that ubiquinol can mildly reduce warfarin’s efficacy, probably by affecting liver enzyme activity or the plasma protein binding. If you’re on warfarin and consider adding coq10, keep an eye on your INR and talk to a provider before making any changes. I’ve checked with my doctor and we’re just monitoring closely – nothing drastic has happened yet.

Community discussion - research and educational context only. Not medical advice.