ResearchSafe

Oxandrolone and my HDL drop – is this typical?

Posted by ethan_hrv in Safety & Side Effects - 2 points, 4 comments.

Not gonna lie, i started oxandrolone about six weeks ago for a lean bulk, keeping the dose at 20 mg split twice a day, and my last lipid panel shows a lower HDL than before. I was surprised because the literature says it usually lowers HDL but my medical school says steroid use can mess with lipids. I did a quick google on the /peptides/oxandrolone page that shows the side effect list includes “lipid disruption (HDL decrease)”, so maybe i’m just seeing the expected effect.

RIENDS, any of you have seen a similar drop and how did you handle it? Did you monitor your lipid panel more often, or do a different supplement approach? I appreciate any real experiences or safety tips i can use to keep this moving safely.

Comments

  • greg208: Not gonna lie, I’ve seen a similar dip when I was on low‑dose oxandrolone for a lean bulk back in 2014, about 3 mg a day for a month. My HDL fell by around 5 mg/dL and it stayed low for a few weeks after stopping. I kept an eye on it – checked a repeat panel after 4 weeks off the drug – it edged back up. I didn’t tweak my diet big time, just added a bit more omega‑3 fish oil, and it seemed to help smooth the swing. How long after you’ve cut the steroid are you waiting for a repeat test?
  • aspiring_trailrun: I had a similar dip after about 4 weeks of 20 mg split. I waited a month before re‑checking and added a 1‑gram fish‑oil daily. My HDL crept back up within 5 weeks. özü what dose were you running when you saw the drop?
  • ethan_hrv: Not gonna lie, i was on 20mg split then. You added fish oil? Did it take longer for you or did it bounce back fast? I’m still weighing if i should wait longer or tweak the dose.
  • ethan_hrv: Not gonna lie, i stopped oxand at the end of week 6 and plan to re‑check after about 8 weeks off, so it’s a bit longer than your 4‑week window, maybe that explains the continued dip. I’ll add a fish‑oil supplement like you did, but not sure if agb 2 grams EPA/DHA is enough, do you dose more? Did you notice any other lipid changes or side‑effects while waiting?

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