Curious about GDF‑11 dosing and side‑effects for an ex‑firefighter

Posted by greg208 in Longevity & Anti-Aging - 1 points, 0 comments.

Not gonna lie, I've been dabbling with rapamycin and metformin for about two months now, hoping the low‑dose pulsed schedule will boost my immune response and maybe help with the knee pain that still lingers from the old firefighting gear. I’ve read the GDF‑11 page and the idea that it can restore muscle stem cells and even help with neurogenesis sounds tempting, especially since I still feel a bit sluggish after a long shift. 5 mg/kg range used in the animal studies.

I’ve never taken anything like it; this would be my first time. Anyone else here who has tried GDF‑11? How did you manage dosing, and did you notice any mouth sores or GI upset like with rapamycin? Would you pair it with my current metformin regime, or would that complicate things?

Community discussion - research and educational context only. Not medical advice.