ResearchSafe

2C-E (4-Ethyl-2,5-dimethoxyphenethylamine)

Category: Psychedelics. Status: Schedule I (research compound).

A more intense member of the 2C family, known for deep, introspective and strongly visual experiences. Documented in Shulgin's research.

How it works

Activates serotonin 5-HT2A receptors.

Key facts

  • Molecular weight: 209.29 g/mol
  • Half-life: ~2-3 hours
  • Bioavailability: Oral
  • Storage: Research/reference only.

Dosing overview

  • Typical dose: Varies by individual and setting
  • Frequency: Occasional
  • Duration: Acute effects last 6-10 hours
  • Route: Oral

Protocol notes

  • Taken orally; deeper and more introspective than 2C-B, so used in quiet settings.
  • Onset can be slow, which sometimes leads people to redose too early (a mistake).

Reported benefits

  • Deep, introspective effects
  • Strong visuals
  • Shulgin research compound
  • Distinct from 2C-B

Possible side effects

  • Anxiety and confusion
  • Nausea
  • Body load
  • Dose-sensitive

Compare 2C-E

Research and educational reference only. Not medical advice.