Drostanolone Propionate (Drostanolone Propionate (Masteron))
A DHT-derived anabolic steroid (Masteron), historically used against breast cancer and popular in cutting phases for its hardening, anti-estrogenic effect on lean physiques. Educational reference only.
How it works
Drostanolone is derived from dihydrotestosterone (DHT), giving it strong androgenic and modest anabolic activity. It cannot aromatize and has mild anti-estrogenic action, contributing to a "dry, hard" look on lean individuals.
Key facts
- Molecular weight: 360.5 Da
- Half-life: ~2-3 days (propionate)
- Bioavailability: Intramuscular injection
- Storage: Room temperature; protect from light.
Dosing overview
- Typical dose: Used in cutting phases (non-medical)
- Frequency: Every 2-3 days
- Duration: Cycled
- Route: Intramuscular injection
Protocol notes
- The propionate ester requires injections every 2-3 days (an enanthate version exists for less frequent dosing).
- Most visible effect appears on already-lean physiques.
- Provides mild anti-estrogenic effects.
Reported benefits
- Muscle hardening on lean physiques
- Mild anti-estrogenic effect
- No aromatization
- Preserves lean mass in a deficit
Possible side effects
- Androgenic hair loss
- Prostate effects
- Testosterone suppression
- Adverse lipids
- Acne
Research
- Drostanolone in breast cancer (2013): Historically used as an anti-estrogenic agent in hormone-responsive breast cancer before modern therapies.
Community reviews of Drostanolone Propionate
- titrate_tina rated it 5/5 - Solid gains with manageable sides: Ran Drostanolone Propionate for about 2 months at a moderate dose with proper support (AI, liver support, PCT planned). Strength went up noticeably by week 3-4 and body composition improved steadily. Side effects were present but manageable at the dose I ran. Some acne on shoulders, slight mood elevation (positive), and lipids shifted but stayed within an acceptable range per bloodwork. Did not push the dose and I think that made the difference. This is not something to approach without bloodwork, proper cycle support, and a real PCT plan. But used responsibly, the results are undeniable. Re
- subq_samantha rated it 5/5 - Bloodwork stayed reasonable throughout: Drostanolone Propionate delivered on its reputation. Used at a conservative dose because I value health markers over maximum gains. Still got impressive results: strength up across all lifts, muscle fullness noticeably improved, recovery between sessions dramatically better. Side effect management was key. Had my protocols dialed in before starting. Minor androgenic sides (slightly oily skin) that resolved post-cycle. No significant mood issues at my dose. Would I run again? Yes, but with the same conservative approach and mandatory bloodwork. These compounds demand respect and responsibilit
- trough_tracker_tim rated it 5/5 - Results matched expectations at moderate dose: Moderate dose of Drostanolone Propionate for 2 months. Added about 8-12 lbs of lean tissue while body fat stayed stable or dropped slightly. Strength gains were progressive and consistent. Bloodwork at mid-cycle showed suppressed natural production as expected, lipids shifted but not dramatically. Liver values stayed fine. Ran proper cycle support throughout. The compound does what it says. It is not magic and it does not replace hard training and diet, but it amplifies everything you are already doing correctly. PCT brought things back to baseline within 4-6 weeks.
- bac_water_betty rated it 5/5 - Recovery and strength both improved: Ran Drostanolone Propionate for about 1 month at a moderate dose with proper support (AI, liver support, PCT planned). Strength went up noticeably by week 3-4 and body composition improved steadily. Side effects were present but manageable at the dose I ran. Some acne on shoulders, slight mood elevation (positive), and lipids shifted but stayed within an acceptable range per bloodwork. Did not push the dose and I think that made the difference. This is not something to approach without bloodwork, proper cycle support, and a real PCT plan. But used responsibly, the results are undeniable. Rec
- peptide_path_pam rated it 4/5 - Effective when respect the compound: Moderate dose of Drostanolone Propionate for 3 weeks. Added about 8-12 lbs of lean tissue while body fat stayed stable or dropped slightly. Strength gains were progressive and consistent. Bloodwork at mid-cycle showed suppressed natural production as expected, lipids shifted but not dramatically. Liver values stayed fine. Ran proper cycle support throughout. The compound does what it says. It is not magic and it does not replace hard training and diet, but it amplifies everything you are already doing correctly. PCT brought things back to baseline within 4-6 weeks.
Compare Drostanolone Propionate
Community discussions about Drostanolone Propionate
- Feedback on a 8‑week cutting stack with Testosterone Propionate, Drostanolone and KLOW - 4 comments
- Ask the community about Drostanolone Propionate
Research and educational reference only. Not medical advice.