Glutathione (IV/IM) (L-Glutathione (Reduced, Injectable))
The body's master antioxidant administered via IV or intramuscular injection for maximum bioavailability. Bypasses the poor oral absorption of glutathione to directly raise intracellular GSH levels for detoxification, immune support, and skin brightening.
How it works
Directly conjugates with toxins, heavy metals, and reactive oxygen species via glutathione S-transferases. Regenerates vitamins C and E. Maintains thiol redox status. Supports Phase II liver detoxification.
Key facts
- Molecular weight: 307.32 Da
- Half-life: ~2-3 hours (IV bolus)
- Bioavailability: 100% (IV); ~60% (IM); ~5-10% (oral)
- Storage: Refrigerate (2-8°C). Protect from light. Use within 24h once drawn.
Dosing overview
- Typical dose: 600-2000 mg IV push or 200-600 mg IM
- Frequency: 1-3x weekly
- Duration: 8-12 week cycles
- Route: Intravenous push or intramuscular injection
Reported benefits
- Heavy metal detoxification
- Liver support and protection
- Skin brightening/lightening
- Immune system enhancement
- Mitochondrial protection
- Anti-aging (oxidative stress reduction)
Possible side effects
- Sulfur taste during IV push
- Mild headache
- Zinc depletion (long-term)
- Rare: bloating/cramping
- Transient drop in blood pressure (fast push)
Research
- IV glutathione and Parkinson's disease (2020): IV GSH (1400mg 3x/week) improved motor function scores by 25% in early PD patients over 4-week trial.
- Glutathione and oxidative stress biomarkers (2021): 1000mg IV glutathione acutely reduced malondialdehyde by 40% and increased antioxidant capacity for 24h post-infusion.
Compare Glutathione (IV/IM)
Research and educational reference only. Not medical advice.